CovidV1, Main, Exploration, bibRecord, 000C24

Synthesis, antiviral and cytotoxic investigation of 2-phenyl-3-substituted quinazolin-4(3H)-ones.

Identifieur interne : 000C24 ( Main/Exploration ); précédent : 000C23; suivant : 000C25

Synthesis, antiviral and cytotoxic investigation of 2-phenyl-3-substituted quinazolin-4(3H)-ones.

Auteurs : S K Krishnan [Inde] ; S. Ganguly ; R. Veerasamy ; B. Jan

Source :

European review for medical and pharmacological sciences [ 1128-3602 ] ; 2011.

RBID : pubmed:21796872

Descripteurs français

KwdFr :
- Animaux, Antiviraux (pharmacologie), Antiviraux (synthèse chimique), Antiviraux (toxicité), Cellules HeLa, Cellules Vero, Chats, Chiens, Humains, Lignée cellulaire, Maladies virales (traitement médicamenteux), Maladies virales (virologie), Quinazolinones (pharmacologie), Quinazolinones (synthèse chimique), Quinazolinones (toxicité), Relation structure-activité, Réplication virale ().
MESH :
- pharmacologie : Antiviraux, Quinazolinones.
- synthèse chimique : Antiviraux, Quinazolinones.
- toxicité : Antiviraux, Quinazolinones.
- traitement médicamenteux : Maladies virales.
- virologie : Maladies virales.
- Animaux, Cellules HeLa, Cellules Vero, Chats, Chiens, Humains, Lignée cellulaire, Relation structure-activité, Réplication virale.

English descriptors

KwdEn :
- Animals, Antiviral Agents (chemical synthesis), Antiviral Agents (pharmacology), Antiviral Agents (toxicity), Cats, Cell Line, Chlorocebus aethiops, Dogs, HeLa Cells, Humans, Quinazolinones (chemical synthesis), Quinazolinones (pharmacology), Quinazolinones (toxicity), Structure-Activity Relationship, Vero Cells, Virus Diseases (drug therapy), Virus Diseases (virology), Virus Replication (drug effects).
MESH :
- chemical , chemical synthesis : Antiviral Agents, Quinazolinones.
- chemical , pharmacology : Antiviral Agents, Quinazolinones.
- chemical , toxicity : Antiviral Agents, Quinazolinones.
- drug effects : Virus Replication.
- drug therapy : Virus Diseases.
- virology : Virus Diseases.
- Animals, Cats, Cell Line, Chlorocebus aethiops, Dogs, HeLa Cells, Humans, Structure-Activity Relationship, Vero Cells.

Abstract

A series of 3(benzylideneamino)-2-phenyl quinazoline-4(3H)-ones was synthesized by reaction of 3-amino-2-phenyl-3H-quinazoline-4-one with various carbonyl compounds.

PubMed: 21796872

Affiliations:

Inde

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Synthesis, antiviral and cytotoxic investigation of 2-phenyl-3-substituted quinazolin-4(3H)-ones.</title>
<author><name sortKey="Krishnan, S K" sort="Krishnan, S K" uniqKey="Krishnan S" first="S K" last="Krishnan">S K Krishnan</name>
<affiliation wicri:level="1"><nlm:affiliation>Medicinal Chemistry Research Laboratory, KMCH College of Pharmacy, Coimbatore, India. pharmsuki@gmail.com</nlm:affiliation>
<country xml:lang="fr">Inde</country>
<wicri:regionArea>Medicinal Chemistry Research Laboratory, KMCH College of Pharmacy, Coimbatore</wicri:regionArea>
<wicri:noRegion>Coimbatore</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ganguly, S" sort="Ganguly, S" uniqKey="Ganguly S" first="S" last="Ganguly">S. Ganguly</name>
</author>
<author><name sortKey="Veerasamy, R" sort="Veerasamy, R" uniqKey="Veerasamy R" first="R" last="Veerasamy">R. Veerasamy</name>
</author>
<author><name sortKey="Jan, B" sort="Jan, B" uniqKey="Jan B" first="B" last="Jan">B. Jan</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2011">2011</date>
<idno type="RBID">pubmed:21796872</idno>
<idno type="pmid">21796872</idno>
<idno type="wicri:Area/PubMed/Corpus">000667</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000667</idno>
<idno type="wicri:Area/PubMed/Curation">000667</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000667</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000662</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000662</idno>
<idno type="wicri:Area/Ncbi/Merge">000233</idno>
<idno type="wicri:Area/Ncbi/Curation">000233</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000233</idno>
<idno type="wicri:doubleKey">1128-3602:2011:Krishnan S:synthesis:antiviral:and</idno>
<idno type="wicri:Area/Main/Merge">000C26</idno>
<idno type="wicri:Area/Main/Curation">000C24</idno>
<idno type="wicri:Area/Main/Exploration">000C24</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Synthesis, antiviral and cytotoxic investigation of 2-phenyl-3-substituted quinazolin-4(3H)-ones.</title>
<author><name sortKey="Krishnan, S K" sort="Krishnan, S K" uniqKey="Krishnan S" first="S K" last="Krishnan">S K Krishnan</name>
<affiliation wicri:level="1"><nlm:affiliation>Medicinal Chemistry Research Laboratory, KMCH College of Pharmacy, Coimbatore, India. pharmsuki@gmail.com</nlm:affiliation>
<country xml:lang="fr">Inde</country>
<wicri:regionArea>Medicinal Chemistry Research Laboratory, KMCH College of Pharmacy, Coimbatore</wicri:regionArea>
<wicri:noRegion>Coimbatore</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ganguly, S" sort="Ganguly, S" uniqKey="Ganguly S" first="S" last="Ganguly">S. Ganguly</name>
</author>
<author><name sortKey="Veerasamy, R" sort="Veerasamy, R" uniqKey="Veerasamy R" first="R" last="Veerasamy">R. Veerasamy</name>
</author>
<author><name sortKey="Jan, B" sort="Jan, B" uniqKey="Jan B" first="B" last="Jan">B. Jan</name>
</author>
</analytic>
<series><title level="j">European review for medical and pharmacological sciences</title>
<idno type="ISSN">1128-3602</idno>
<imprint><date when="2011" type="published">2011</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term>
<term>Antiviral Agents (chemical synthesis)</term>
<term>Antiviral Agents (pharmacology)</term>
<term>Antiviral Agents (toxicity)</term>
<term>Cats</term>
<term>Cell Line</term>
<term>Chlorocebus aethiops</term>
<term>Dogs</term>
<term>HeLa Cells</term>
<term>Humans</term>
<term>Quinazolinones (chemical synthesis)</term>
<term>Quinazolinones (pharmacology)</term>
<term>Quinazolinones (toxicity)</term>
<term>Structure-Activity Relationship</term>
<term>Vero Cells</term>
<term>Virus Diseases (drug therapy)</term>
<term>Virus Diseases (virology)</term>
<term>Virus Replication (drug effects)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term>
<term>Antiviraux (pharmacologie)</term>
<term>Antiviraux (synthèse chimique)</term>
<term>Antiviraux (toxicité)</term>
<term>Cellules HeLa</term>
<term>Cellules Vero</term>
<term>Chats</term>
<term>Chiens</term>
<term>Humains</term>
<term>Lignée cellulaire</term>
<term>Maladies virales (traitement médicamenteux)</term>
<term>Maladies virales (virologie)</term>
<term>Quinazolinones (pharmacologie)</term>
<term>Quinazolinones (synthèse chimique)</term>
<term>Quinazolinones (toxicité)</term>
<term>Relation structure-activité</term>
<term>Réplication virale ()</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="chemical synthesis" xml:lang="en"><term>Antiviral Agents</term>
<term>Quinazolinones</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Antiviral Agents</term>
<term>Quinazolinones</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="toxicity" xml:lang="en"><term>Antiviral Agents</term>
<term>Quinazolinones</term>
</keywords>
<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Virus Replication</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Virus Diseases</term>
</keywords>
<keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Antiviraux</term>
<term>Quinazolinones</term>
</keywords>
<keywords scheme="MESH" qualifier="synthèse chimique" xml:lang="fr"><term>Antiviraux</term>
<term>Quinazolinones</term>
</keywords>
<keywords scheme="MESH" qualifier="toxicité" xml:lang="fr"><term>Antiviraux</term>
<term>Quinazolinones</term>
</keywords>
<keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Maladies virales</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Maladies virales</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Virus Diseases</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Cats</term>
<term>Cell Line</term>
<term>Chlorocebus aethiops</term>
<term>Dogs</term>
<term>HeLa Cells</term>
<term>Humans</term>
<term>Structure-Activity Relationship</term>
<term>Vero Cells</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Animaux</term>
<term>Cellules HeLa</term>
<term>Cellules Vero</term>
<term>Chats</term>
<term>Chiens</term>
<term>Humains</term>
<term>Lignée cellulaire</term>
<term>Relation structure-activité</term>
<term>Réplication virale</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">A series of 3(benzylideneamino)-2-phenyl quinazoline-4(3H)-ones was synthesized by reaction of 3-amino-2-phenyl-3H-quinazoline-4-one with various carbonyl compounds.</div>
</front>
</TEI>
<affiliations><list><country><li>Inde</li>
</country>
</list>
<tree><noCountry><name sortKey="Ganguly, S" sort="Ganguly, S" uniqKey="Ganguly S" first="S" last="Ganguly">S. Ganguly</name>
<name sortKey="Jan, B" sort="Jan, B" uniqKey="Jan B" first="B" last="Jan">B. Jan</name>
<name sortKey="Veerasamy, R" sort="Veerasamy, R" uniqKey="Veerasamy R" first="R" last="Veerasamy">R. Veerasamy</name>
</noCountry>
<country name="Inde"><noRegion><name sortKey="Krishnan, S K" sort="Krishnan, S K" uniqKey="Krishnan S" first="S K" last="Krishnan">S K Krishnan</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/CovidV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000C24 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000C24 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Sante
   |area=    CovidV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:21796872
   |texte=   Synthesis, antiviral and cytotoxic investigation of 2-phenyl-3-substituted quinazolin-4(3H)-ones.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:21796872" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a CovidV1

This area was generated with Dilib version V0.6.33.
Data generation: Fri Mar 27 18:14:15 2020. Site generation: Sun Jan 31 15:15:08 2021

Serveur d'exploration Covid

Synthesis, antiviral and cytotoxic investigation of 2-phenyl-3-substituted quinazolin-4(3H)-ones.

Synthesis, antiviral and cytotoxic investigation of 2-phenyl-3-substituted quinazolin-4(3H)-ones.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration Covid
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.